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Dynamic Rearrangement of F-Actin Is Required to Maintain the Antitumor Effect of Trichostatin A
Actin plays a role in various processes in eukaryotic cells, including cell growth and death. We investigated whether the antitumor effect of trichostatin A (TSA) is associated with the dynamic rearrangement of F-actin. TSA is an antitumor drug that induces hyper-acetylation of histones by inhibitin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028200/ https://www.ncbi.nlm.nih.gov/pubmed/24846135 http://dx.doi.org/10.1371/journal.pone.0097352 |