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Normal Fibroblasts Induce E-Cadherin Loss and Increase Lymph Node Metastasis in Gastric Cancer

BACKGROUND: A tumor is considered a heterogeneous complex in a three-dimensional environment that is flush with pathophysiological and biomechanical signals. Cell-stroma interactions guide the development and generation of tumors. Here, we evaluate the contributions of normal fibroblasts to gastric...

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Detalles Bibliográficos
Autores principales: Xu, Wen, Hu, Xinlei, Chen, Zhongting, Zheng, Xiaoping, Zhang, Chenjing, Wang, Gang, Chen, Yu, Zhou, Xinglu, Tang, Xiaoxiao, Luo, Laisheng, Xu, Xiang, Pan, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028202/
https://www.ncbi.nlm.nih.gov/pubmed/24845259
http://dx.doi.org/10.1371/journal.pone.0097306