Nrf2-Inducing Anti-Oxidation Stress Response in the Rat Liver - New Beneficial Effect of Lansoprazole

Lansoprazole is a potent anti-gastric ulcer drug that inhibits gastric proton pump activity. We identified a novel function for lansoprazole, as an inducer of anti-oxidative stress responses in the liver. Gastric administration of lansoprazole (10–100 mg/kg) to male Wistar rats produced a dose-depen...

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Detalles Bibliográficos
Autores principales: Yamashita, Yasunobu, Ueyama, Takashi, Nishi, Toshio, Yamamoto, Yuta, Kawakoshi, Akatsuki, Sunami, Shogo, Iguchi, Mikitaka, Tamai, Hideyuki, Ueda, Kazuki, Ito, Takao, Tsuruo, Yoshihiro, Ichinose, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028208/
https://www.ncbi.nlm.nih.gov/pubmed/24846271
http://dx.doi.org/10.1371/journal.pone.0097419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028208/
https://www.ncbi.nlm.nih.gov/pubmed/24846271
http://dx.doi.org/10.1371/journal.pone.0097419

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