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Designing Anti-Influenza Aptamers: Novel Quantitative Structure Activity Relationship Approach Gives Insights into Aptamer – Virus Interaction

This study describes the development of aptamers as a therapy against influenza virus infection. Aptamers are oligonucleotides (like ssDNA or RNA) that are capable of binding to a variety of molecular targets with high affinity and specificity. We have studied the ssDNA aptamer BV02, which was desig...

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Detalles Bibliográficos
Autores principales: Musafia, Boaz, Oren-Banaroya, Rony, Noiman, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028238/
https://www.ncbi.nlm.nih.gov/pubmed/24846127
http://dx.doi.org/10.1371/journal.pone.0097696