The Epigenetic Bivalency of Core Pancreatic β-Cell Transcription Factor Genes within Mouse Pluripotent Embryonic Stem Cells Is Not Affected by Knockdown of the Polycomb Repressive Complex 2, SUZ12

This study assesses changes in activator and repressor modifications to histones associated with the core transcription factor genes most highly upregulated or downregulated in pancreatic β-cells relative to expression in an embryonic stem cell line. Epigenetic analysis of the Oct4, Utf1, Nanog and...

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Detalles Bibliográficos
Autores principales: Wong, Jennifer C. Y., Jack, Michelle M., Li, Yan, O'Neill, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028244/
https://www.ncbi.nlm.nih.gov/pubmed/24845830
http://dx.doi.org/10.1371/journal.pone.0097820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028244/
https://www.ncbi.nlm.nih.gov/pubmed/24845830
http://dx.doi.org/10.1371/journal.pone.0097820

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