Human Motor Neurons Generated from Neural Stem Cells Delay Clinical Onset and Prolong Life in ALS Mouse Model

Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease. The etiology and pathogenic mechanisms of the disease remain unknown, and there is no effective treatment. Here we show that intrathecal transplantation of human motor neurons derived from neural stem cells (NSC...

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Detalles Bibliográficos
Autores principales: Lee, Hong J., Kim, Kwang S., Ahn, Jin, Bae, Hye M., Lim, Inja, Kim, Seung U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028267/
https://www.ncbi.nlm.nih.gov/pubmed/24844281
http://dx.doi.org/10.1371/journal.pone.0097518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028267/
https://www.ncbi.nlm.nih.gov/pubmed/24844281
http://dx.doi.org/10.1371/journal.pone.0097518

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