Mice Deficient in Transmembrane Prostatic Acid Phosphatase Display Increased GABAergic Transmission and Neurological Alterations

Prostatic acid phosphatase (PAP), the first diagnostic marker and present therapeutic target for prostate cancer, modulates nociception at the dorsal root ganglia (DRG), but its function in the central nervous system has remained unknown. We studied expression and function of TMPAP (the transmembran...

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Detalles Bibliográficos
Autores principales: Nousiainen, Heidi O., Quintero, Ileana B., Myöhänen, Timo T., Voikar, Vootele, Mijatovic, Jelena, Segerstråle, Mikael, Herrala, Annakaisa M., Kulesskaya, Natalia, Pulkka, Anitta E., Kivinummi, Tanja, Abo-Ramadan, Usama, Taira, Tomi, Piepponen, T. Petteri, Rauvala, Heikki, Vihko, Pirkko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028278/
https://www.ncbi.nlm.nih.gov/pubmed/24846136
http://dx.doi.org/10.1371/journal.pone.0097851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028278/
https://www.ncbi.nlm.nih.gov/pubmed/24846136
http://dx.doi.org/10.1371/journal.pone.0097851

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