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Mice Deficient in Transmembrane Prostatic Acid Phosphatase Display Increased GABAergic Transmission and Neurological Alterations
Prostatic acid phosphatase (PAP), the first diagnostic marker and present therapeutic target for prostate cancer, modulates nociception at the dorsal root ganglia (DRG), but its function in the central nervous system has remained unknown. We studied expression and function of TMPAP (the transmembran...
Autores principales: | Nousiainen, Heidi O., Quintero, Ileana B., Myöhänen, Timo T., Voikar, Vootele, Mijatovic, Jelena, Segerstråle, Mikael, Herrala, Annakaisa M., Kulesskaya, Natalia, Pulkka, Anitta E., Kivinummi, Tanja, Abo-Ramadan, Usama, Taira, Tomi, Piepponen, T. Petteri, Rauvala, Heikki, Vihko, Pirkko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028278/ https://www.ncbi.nlm.nih.gov/pubmed/24846136 http://dx.doi.org/10.1371/journal.pone.0097851 |
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