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Downregulation of HIPK2 Increases Resistance of Bladder Cancer Cell to Cisplatin by Regulating Wip1

Cisplatin-based combination chemotherapy regimen is a reasonable alternative to cystectomy in advanced/metastatic bladder cancer, but acquisition of cisplatin resistance is common in patients with bladder cancer. Previous studies showed that loss of homeodomain-interacting protein kinase-2 (HIPK2) c...

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Detalles Bibliográficos
Autores principales: Lin, Jun, Zhang, Qiang, Lu, Yi, Xue, Wenrui, Xu, Yue, Zhu, Yichen, Hu, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028303/
https://www.ncbi.nlm.nih.gov/pubmed/24846322
http://dx.doi.org/10.1371/journal.pone.0098418