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Downregulation of HIPK2 Increases Resistance of Bladder Cancer Cell to Cisplatin by Regulating Wip1
Cisplatin-based combination chemotherapy regimen is a reasonable alternative to cystectomy in advanced/metastatic bladder cancer, but acquisition of cisplatin resistance is common in patients with bladder cancer. Previous studies showed that loss of homeodomain-interacting protein kinase-2 (HIPK2) c...
Autores principales: | Lin, Jun, Zhang, Qiang, Lu, Yi, Xue, Wenrui, Xu, Yue, Zhu, Yichen, Hu, Xiaopeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028303/ https://www.ncbi.nlm.nih.gov/pubmed/24846322 http://dx.doi.org/10.1371/journal.pone.0098418 |
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