Protonated Form: The Potent Form of Potassium-Competitive Acid Blockers

Potassium-competitive acid blockers (P-CABs) are highly safe and active drugs targeting H(+),K(+)-ATPase to cure acid-related gastric diseases. In this study, we for the first time investigate the interaction mechanism between the protonated form of P-CABs and human H(+),K(+)-ATPase using homology m...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Hua-Jun, Deng, Wei-Qiao, Zou, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028304/
https://www.ncbi.nlm.nih.gov/pubmed/24845980
http://dx.doi.org/10.1371/journal.pone.0097688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028304/
https://www.ncbi.nlm.nih.gov/pubmed/24845980
http://dx.doi.org/10.1371/journal.pone.0097688

Ejemplares similares