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Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis

Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-β1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs including skin, liver, kidney, and lung. Thus, TGF-β1 and its signaling pathways have been at...

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Detalles Bibliográficos
Autores principales: Lee, Chang-Min, Park, Jin Wook, Cho, Won-Kyung, Zhou, Yang, Han, Boram, Yoon, Pyoung Oh, Chae, Jeiwook, Elias, Jack A, Lee, Chun Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028515/
https://www.ncbi.nlm.nih.gov/pubmed/24851060
http://dx.doi.org/10.3904/kjim.2014.29.3.281