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Macrophages promote polycystic kidney disease progression

Renal M2-like macrophages have critical roles in tissue repair stimulating tubule cell proliferation and, if they remain, fibrosis. M2-like macrophages have also been implicated in promoting cyst expansion in mouse models of autosomal dominant polycystic kidney disease (ADPKD). While renal macrophag...

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Detalles Bibliográficos
Autores principales: Swenson-Fields, Katherine I., Vivian, Carolyn J., Salah, Sally M., Peda, Jacqueline D., Davis, Bradley M., van Rooijen, Nico, Wallace, Darren P., Fields, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028685/
https://www.ncbi.nlm.nih.gov/pubmed/23423256
http://dx.doi.org/10.1038/ki.2012.446