The PI3K/AKT Pathway and FOXO3a Transcription Factor Mediate High Glucose-Induced Apoptosis in Neonatal Rat Ventricular Myocytes

BACKGROUND: PI3K/AKT pathway plays major roles in regulating cardiomyocyte metabolism. The roles of PI3K/AKT pathway and FOXO3a in mediating high glucose-induced apoptosis in cardiomyocytes remain unclear. OBJECTIVES: In this experimental study, we investigated the mechanisms of the PI3K/AKT pathway...

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Detalles Bibliográficos
Autores principales: Bao, Weiguo, Pan, Feng, Chen, Ling, Su, Guohai, Gao, Xiaoyuan, Li, Ying, Sun, Qiang, Sun, Jinhui, He, Kun, Song, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028775/
https://www.ncbi.nlm.nih.gov/pubmed/24910802
http://dx.doi.org/10.5812/ircmj.14914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028775/
https://www.ncbi.nlm.nih.gov/pubmed/24910802
http://dx.doi.org/10.5812/ircmj.14914

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