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Activation of transsulfuration pathway by salvianolic acid a treatment: a homocysteine-lowering approach with beneficial effects on redox homeostasis in high-fat diet-induced hyperlipidemic rats

BACKGROUND: Elevated homocysteine is a cardiovascular risk factor in hyperlipidemia. Transsulfuration pathway provides an endogenous pathway for homocysteine conversion to antioxidant glutathione (GSH). Salvianolic acid A (Sal A) contains two molecules of caffeic acid and one molecule of danshensu t...

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Detalles Bibliográficos
Autores principales: Zhang, Wenting, He, Hua, Wang, Haidong, Wang, Shijun, Li, Xi, Liu, Yao, Jiang, Huiyong, Jiang, Hao, Yan, Yidan, Wang, Yixuan, Liu, Xiaoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028786/
https://www.ncbi.nlm.nih.gov/pubmed/24314320
http://dx.doi.org/10.1186/1743-7075-10-68