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FISH(+)CD34(+)CD38(-) cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome

BACKGROUND: In acute myeloid leukemia (AML), the leukemia initiating cells (LICs) or leukemia stem cells (LSCs) is found within the CD34(+)CD38(-) cell compartment. The LICs subpopulation survives chemotherapy and is most probable the cause of minimal residual disease (MRD), which in turn is thought...

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Detalles Bibliográficos
Autores principales: Wang, Libing, Gao, Lei, Xu, Sheng, Gong, Shenglan, Chen, Li, Lü, Shuqing, Chen, Jie, Qiu, Huiying, Xu, Xiaoqian, Ni, Xiong, Song, Xianmin, Zhang, Weiping, Yang, Jianmin, Liu, Min, Hu, Xiaoxia, Wang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028871/
https://www.ncbi.nlm.nih.gov/pubmed/24517186
http://dx.doi.org/10.1186/1756-8722-6-85