Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

Although the process of drug development requires efficacy and toxicity testing in animals prior to human testing, animal models have limited ability to accurately predict human responses to xenobiotics and other insults. Societal pressures are also focusing on reduction of and, ultimately, replacem...

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Detalles Bibliográficos
Autores principales: Bhushan, Abhinav, Senutovitch, Nina, Bale, Shyam S, McCarty, William J, Hegde, Manjunath, Jindal, Rohit, Golberg, Inna, Berk Usta, O, Yarmush, Martin L, Vernetti, Lawrence, Gough, Albert, Bakan, Ahmet, Shun, Tong Ying, Biasio, Richard, Lansing Taylor, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028964/
https://www.ncbi.nlm.nih.gov/pubmed/24565476
http://dx.doi.org/10.1186/scrt377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028964/
https://www.ncbi.nlm.nih.gov/pubmed/24565476
http://dx.doi.org/10.1186/scrt377

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