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Two different network topologies yield bistability in models of mesoderm and anterior mesendoderm specification in amphibians

Understanding the Gene Regulatory Networks (GRNs) that underlie development is a major question for systems biology. The establishment of the germ layers is amongst the earliest events of development and has been characterised in numerous model systems. The establishment of the mesoderm is best char...

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Detalles Bibliográficos
Autores principales: Brown, L.E., King, J.R., Loose, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029075/
https://www.ncbi.nlm.nih.gov/pubmed/24650939
http://dx.doi.org/10.1016/j.jtbi.2014.03.015