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Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation

Gastrulation generates three layers of cells (ectoderm, mesoderm, endoderm) from a single sheet, while large scale cell movements occur across the entire embryo. In amniote (reptiles, birds, mammals) embryos, the deep layers arise by epithelial-to-mesenchymal transition (EMT) at a morphologically st...

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Detalles Bibliográficos
Autores principales: Voiculescu, Octavian, Bodenstein, Lawrence, Lau, I-Jun, Stern, Claudio D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029171/
https://www.ncbi.nlm.nih.gov/pubmed/24850665
http://dx.doi.org/10.7554/eLife.01817