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Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data

BACKGROUND: Chromatin immunoprecipitation (ChIP) experiments are now the most comprehensive experimental approaches for mapping the binding of transcription factors (TFs) to their target genes. However, ChIP data alone is insufficient for identifying functional binding target genes of TFs for two re...

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Detalles Bibliográficos
Autores principales: Yang, Tzu-Hsien, Wu, Wei-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029220/
https://www.ncbi.nlm.nih.gov/pubmed/24565265
http://dx.doi.org/10.1186/1752-0509-7-S6-S13