Comparative preclinical pharmacokinetics study of 3,3′-diindolylmethane formulations: is personalized treatment and targeted chemoprevention in the horizon?

BACKGROUND: 3,3′-Diindolylmethane (DIM) is known as an agent of natural origin that provides protection against different cancers due to the broad spectrum of its biological activities in vivo. However, this substance has a very poor biodistribution and absorption in animal tissues. This preclinical...

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Detalles Bibliográficos
Autores principales: Paltsev, Mikhail, Kiselev, Vsevolod, Muyzhnek, Ekaterina, Drukh, Vadim, Kuznetsov, Igor, Pchelintseva, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029298/
https://www.ncbi.nlm.nih.gov/pubmed/24325835
http://dx.doi.org/10.1186/1878-5085-4-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029298/
https://www.ncbi.nlm.nih.gov/pubmed/24325835
http://dx.doi.org/10.1186/1878-5085-4-25

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