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Quantifying circulating hypoxia-induced RNA transcripts in maternal blood to determine in utero fetal hypoxic status

BACKGROUND: Hypoxia in utero can lead to stillbirth and severe perinatal injury. While current prenatal tests can identify fetuses that are hypoxic, none can determine the severity of hypoxia/acidemia. We hypothesized a hypoxic/acidemic fetus would up-regulate and release hypoxia-induced mRNA from t...

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Detalles Bibliográficos
Autores principales: Whitehead, Clare, Teh, Wan Tinn, Walker, Susan P, Leung, Cheryl, Mendis, Sonali, Larmour, Luke, Tong, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029381/
https://www.ncbi.nlm.nih.gov/pubmed/24314237
http://dx.doi.org/10.1186/1741-7015-11-256