Mutational analysis of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in the interior division of Sabah, Malaysia

BACKGROUND: The sulphadoxine/pyrimethamine (SDX/PYR) combination had been chosen to treat uncomplicated falciparum malaria in Malaysia for more than 30 years. Non-silent mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes are responsible for the resistance to pyrime...

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Detalles Bibliográficos
Autores principales: Lau, Tiek Ying, Sylvi, Mersumpin, William, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029390/
https://www.ncbi.nlm.nih.gov/pubmed/24321120
http://dx.doi.org/10.1186/1475-2875-12-445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029390/
https://www.ncbi.nlm.nih.gov/pubmed/24321120
http://dx.doi.org/10.1186/1475-2875-12-445

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