Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres

The NF-kB family of transcription factors is up-regulated in inflammation and different cancers. Recent data described heterozygous deletions of the NF-kB Inhibitor alpha gene (NFKBIA) in about 20% of glioblastomas (GBM): deletions were mutually exclusive with epidermal growth factor receptor (EGFR)...

Descripción completa

Detalles Bibliográficos
Autores principales: Patanè, Monica, Porrati, Paola, Bottega, Elisa, Morosini, Sara, Cantini, Gabriele, Girgenti, Vita, Rizzo, Ambra, Eoli, Marica, Pollo, Bianca, Sciacca, Francesca L, Pellegatta, Serena, Finocchiaro, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029392/
https://www.ncbi.nlm.nih.gov/pubmed/24330732
http://dx.doi.org/10.1186/1476-4598-12-160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029392/
https://www.ncbi.nlm.nih.gov/pubmed/24330732
http://dx.doi.org/10.1186/1476-4598-12-160

Ejemplares similares