Cargando…

Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres

The NF-kB family of transcription factors is up-regulated in inflammation and different cancers. Recent data described heterozygous deletions of the NF-kB Inhibitor alpha gene (NFKBIA) in about 20% of glioblastomas (GBM): deletions were mutually exclusive with epidermal growth factor receptor (EGFR)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patanè, Monica, Porrati, Paola, Bottega, Elisa, Morosini, Sara, Cantini, Gabriele, Girgenti, Vita, Rizzo, Ambra, Eoli, Marica, Pollo, Bianca, Sciacca, Francesca L, Pellegatta, Serena, Finocchiaro, Gaetano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029392/ https://www.ncbi.nlm.nih.gov/pubmed/24330732 http://dx.doi.org/10.1186/1476-4598-12-160

Ejemplares similares

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma
por: Speranza, Maria Carmela, et al.
Publicado: (2012)

B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres
por: Nehama, Dean, et al.
Publicado: (2019)

Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma
por: Tunici, Patrizia, et al.
Publicado: (2004)

Deciphering the Labyrinthine System of the Immune Microenvironment in Recurrent Glioblastoma: Recent Original Advances and Lessons from Clinical Immunotherapeutic Approaches
por: Anghileri, Elena, et al.
Publicado: (2021)

Prognostic Value of CD109+ Circulating Endothelial Cells in Recurrent Glioblastomas Treated with Bevacizumab and Irinotecan
por: Cuppini, Lucia, et al.
Publicado: (2013)

ABCC3 Expressed by CD56(dim) CD16(+) NK Cells Predicts Response in Glioblastoma Patients Treated with Combined Chemotherapy and Dendritic Cell Immunotherapy
por: Pellegatta, Serena, et al.
Publicado: (2019)

The natural killer cell response and tumor debulking are associated with prolonged survival in recurrent glioblastoma patients receiving dendritic cells loaded with autologous tumor lysates
por: Pellegatta, Serena, et al.
Publicado: (2013)

P12. Combination of radiotherapy and chemotherapy with dendritic cell immunotherapy in glioblastoma patients induces NK and NKT cell responses
por: Pellegatta, S, et al.
Publicado: (2014)

Advanced MRI Assessment during Dendritic Cell Immunotherapy Added to Standard Treatment against Glioblastoma
por: Cuccarini, Valeria, et al.
Publicado: (2019)

Revisiting the Immunological Aspects of Temozolomide Considering the Genetic Landscape and the Immune Microenvironment Composition of Glioblastoma
por: Di Ianni, Natalia, et al.
Publicado: (2021)

Identification of a NFKBIA polymorphism associated with lower NFKBIA protein levels and poor survival outcomes in patients with glioblastoma multiforme
por: ZHAO, ZHAOHUI, et al.
Publicado: (2014)

Cryopreservation of Neurospheres Derived from Human Glioblastoma Multiforme
por: Chong, Yuk-Kien, et al.
Publicado: (2009)

Parametric Response Maps of Perfusion MRI May Identify Recurrent Glioblastomas Responsive to Bevacizumab and Irinotecan
por: Aquino, Domenico, et al.
Publicado: (2014)

Expansion of effector and memory T cells is associated with increased survival in recurrent glioblastomas treated with dendritic cell immunotherapy
por: Eoli, Marica, et al.
Publicado: (2019)

Survival gain in glioblastoma patients treated with dendritic cell immunotherapy is associated with increased NK but not CD8(+) T cell activation in the presence of adjuvant temozolomide
por: Pellegatta, Serena, et al.
Publicado: (2018)

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration
por: Frattini, Véronique, et al.
Publicado: (2012)

Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres
por: Caldera, Valentina, et al.
Publicado: (2011)

An Optimized Method for Manufacturing a Clinical Scale Dendritic Cell-Based Vaccine for the Treatment of Glioblastoma
por: Nava, Sara, et al.
Publicado: (2012)

Glioblastomas
por: Finocchiaro, Gaetano, et al.
Publicado: (2021)

Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres
por: Ding, Dacheng, et al.
Publicado: (2014)

Targeting NRF2, Regulator of Antioxidant System, to Sensitize Glioblastoma Neurosphere Cells to Radiation-Induced Oxidative Stress
por: Godoy, Paulo R. D. V., et al.
Publicado: (2020)

Dexamethasone-mediated inhibition of Glioblastoma neurosphere dispersal in an ex vivo organotypic neural assay
por: Meleis, Ahmed M., et al.
Publicado: (2017)

Integrated Metabolomics and Transcriptomics Analysis of Monolayer and Neurospheres from Established Glioblastoma Cell Lines
por: Peixoto, Joana, et al.
Publicado: (2021)

In vitro Analysis of Neurospheres Derived from Glioblastoma Primary Culture: A Novel Methodology Paradigm
por: Pavon, Lorena Favaro, et al.
Publicado: (2014)

Tumor-initiating cell frequency is relevant for glioblastoma aggressiveness
por: Richichi, Cristina, et al.
Publicado: (2016)

126 novel mutations in Italian patients with neurofibromatosis type 1
por: Bianchessi, Donatella, et al.
Publicado: (2015)

Early tumour shrinkage as a survival predictor in patients with recurrent glioblastoma treated with bevacizumab in the AVAREG randomized phase II study
por: Brandes, Alba A., et al.
Publicado: (2017)

Novel Curcumin Inspired Bis-Chalcone Promotes Endoplasmic Reticulum Stress and Glioblastoma Neurosphere Cell Death
por: Sansalone, Lorenzo, et al.
Publicado: (2019)

MicroRNA and mRNA Expression Changes in Glioblastoma Cells Cultivated under Conditions of Neurosphere Formation
por: Dymova, Maya A., et al.
Publicado: (2022)

Immunotherapy against the radial glia marker GLAST effectively triggers specific antitumor effectors without autoimmunity
por: Cantini, Gabriele, et al.
Publicado: (2012)

PGE(2) Is Crucial for the Generation of FAST Whole- Tumor-Antigens Loaded Dendritic Cells Suitable for Immunotherapy in Glioblastoma
por: Nava, Sara, et al.
Publicado: (2020)

The integrated landscape of driver genomic alterations in glioblastoma
por: Frattini, Veronique, et al.
Publicado: (2013)

Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9
por: Joseph, Justin V., et al.
Publicado: (2015)

Influence of the Cultivation Conditions of the Glioblastoma Neurosphere on the Expression of MALAT1 and LINCROR Long Non-coding RNA Genes
por: Mazur, D. V., et al.
Publicado: (2023)

The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres
por: Gilder, Andrew S., et al.
Publicado: (2018)

Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma
por: Pellegatta, Serena, et al.
Publicado: (2015)

Deletion and low expression of NFKBIA are associated with poor prognosis in lower-grade glioma patients
por: Kinker, Gabriela Sarti, et al.
Publicado: (2016)

CLRM-08 TARGETING IMMUNE-PAYLOAD TO THE GLIOBLASTOMA TUMOR MICROENVIRONMENT USING A MACROPHAGE-BASED TREATMENT RELYING ON AUTOLOGOUS, GENETICALLY MODIFIED, HEMATOPOIETIC STEM CELL-BASED THERAPY: THE TEM-GBM STUDY (NCT03866109)
por: Eoli, Marica, et al.
Publicado: (2022)

A Radial Glia Gene Marker, Fatty Acid Binding Protein 7 (FABP7), Is Involved in Proliferation and Invasion of Glioblastoma Cells
por: De Rosa, Antonella, et al.
Publicado: (2012)

MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells
por: De Bacco, Francesca, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tkp2ms4osa4va64p21mmk38nmb