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Fusion of Hsp70 to Mage-a1 enhances the potency of vaccine-specific immune responses

BACKGROUND: Heat shock proteins (HSPs) are capable of promoting antigen presentation of chaperoned peptides through interactions with receptors on antigen presenting cells. This property of HSPs suggests a potential function as an adjuvant-free carrier to stimulate immune responses against a covalen...

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Detalles Bibliográficos
Autores principales: Jiang, Juhong, Xie, Dan, Zhang, Wenmin, Xiao, Gang, Wen, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029478/
https://www.ncbi.nlm.nih.gov/pubmed/24314011
http://dx.doi.org/10.1186/1479-5876-11-300