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Fusion of Hsp70 to Mage-a1 enhances the potency of vaccine-specific immune responses
BACKGROUND: Heat shock proteins (HSPs) are capable of promoting antigen presentation of chaperoned peptides through interactions with receptors on antigen presenting cells. This property of HSPs suggests a potential function as an adjuvant-free carrier to stimulate immune responses against a covalen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029478/ https://www.ncbi.nlm.nih.gov/pubmed/24314011 http://dx.doi.org/10.1186/1479-5876-11-300 |