Intrathecal leptin inhibits expression of the P2X(2/3) receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury

BACKGROUND: Leptin, an adipocytokine produced mainly by white adipose tissue, has a broad role in the regulation of neuronal functions. Accumulating evidence has revealed that leptin plays an important role in influencing neuropathic pain, shown recently by the finding that chronic administration of...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xin, Kang, Lumei, Li, Guilin, Zeng, Huihong, Zhang, Lei, Ling, Xiang, Dong, Hui, Liang, Shangdong, Chen, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029482/
https://www.ncbi.nlm.nih.gov/pubmed/24325936
http://dx.doi.org/10.1186/1744-8069-9-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029482/
https://www.ncbi.nlm.nih.gov/pubmed/24325936
http://dx.doi.org/10.1186/1744-8069-9-65

Ejemplares similares