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Multivariate generalized multifactor dimensionality reduction to detect gene-gene interactions

BACKGROUND: Recently, one of the greatest challenges in genome-wide association studies is to detect gene-gene and/or gene-environment interactions for common complex human diseases. Ritchie et al. (2001) proposed multifactor dimensionality reduction (MDR) method for interaction analysis. MDR is a c...

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Detalles Bibliográficos
Autores principales: Choi, Jiin, Park, Taesung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029529/
https://www.ncbi.nlm.nih.gov/pubmed/24565370
http://dx.doi.org/10.1186/1752-0509-7-S6-S15