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Inferring protein domains associated with drug side effects based on drug-target interaction network
BACKGROUND: Most phenotypic effects of drugs are involved in the interactions between drugs and their target proteins, however, our knowledge about the molecular mechanism of the drug-target interactions is very limited. One of challenging issues in recent pharmaceutical science is to identify the u...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029543/ https://www.ncbi.nlm.nih.gov/pubmed/24565527 http://dx.doi.org/10.1186/1752-0509-7-S6-S18 |