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In vitro antifungal activity of farnesyltransferase inhibitors against clinical isolates of Aspergillus and Candida

BACKGROUND: Protein farnesylation is an important tosttranslational modification in fungi. We evaluated the antifungal activity of two farnesyltransferase inhibitors against clinical isolates of Aspergillus and Candida. METHODS: Disk diffusion assay and broth microdilution assay were used to determi...

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Detalles Bibliográficos
Autores principales: Qiao, Jianjun, Gao, Peiping, Jiang, Xiaoling, Fang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029545/
https://www.ncbi.nlm.nih.gov/pubmed/24314136
http://dx.doi.org/10.1186/1476-0711-12-37