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In vitro antifungal activity of farnesyltransferase inhibitors against clinical isolates of Aspergillus and Candida
BACKGROUND: Protein farnesylation is an important tosttranslational modification in fungi. We evaluated the antifungal activity of two farnesyltransferase inhibitors against clinical isolates of Aspergillus and Candida. METHODS: Disk diffusion assay and broth microdilution assay were used to determi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029545/ https://www.ncbi.nlm.nih.gov/pubmed/24314136 http://dx.doi.org/10.1186/1476-0711-12-37 |