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Structural Insights into the Evolution of a Sexy Protein: Novel Topology and Restricted Backbone Flexibility in a Hypervariable Pheromone from the Red-Legged Salamander, Plethodon shermani

In response to pervasive sexual selection, protein sex pheromones often display rapid mutation and accelerated evolution of corresponding gene sequences. For proteins, the general dogma is that structure is maintained even as sequence or function may rapidly change. This phenomenon is well exemplifi...

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Detalles Bibliográficos
Autores principales: Wilburn, Damien B., Bowen, Kathleen E., Doty, Kari A., Arumugam, Sengodagounder, Lane, Andrew N., Feldhoff, Pamela W., Feldhoff, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029566/
https://www.ncbi.nlm.nih.gov/pubmed/24849290
http://dx.doi.org/10.1371/journal.pone.0096975