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Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer

Radiation and drug resistance are significant challenges in the treatment of locally advanced, recurrent and metastatic breast cancer that contribute to mortality. Clinically, radiotherapy requires oxygen to generate cytotoxic free radicals that cause DNA damage and allow that damage to become fixed...

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Detalles Bibliográficos
Autores principales: Thomas, Stefani N., Liao, Zhongping, Clark, David, Chen, Yangyi, Samadani, Ramin, Mao, Li, Ann, David K., Baulch, Janet E., Shapiro, Paul, Yang, Austin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029595/
https://www.ncbi.nlm.nih.gov/pubmed/24860738
http://dx.doi.org/10.3390/proteomes1020087