Cytoplasmic Localization of p21 Protects Trophoblast Giant Cells from DNA Damage Induced Apoptosis

Proliferating trophoblast stem cells (TSCs) can differentiate into nonproliferating but viable trophoblast giant cells (TGCs) that are resistant to DNA damage induced apoptosis. Differentiation is associated with selective up-regulation of the Cip/Kip cyclin-dependent kinase inhibitors p57 and p21;...

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Detalles Bibliográficos
Autores principales: de Renty, Christelle, DePamphilis, Melvin L., Ullah, Zakir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029599/
https://www.ncbi.nlm.nih.gov/pubmed/24848107
http://dx.doi.org/10.1371/journal.pone.0097434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029599/
https://www.ncbi.nlm.nih.gov/pubmed/24848107
http://dx.doi.org/10.1371/journal.pone.0097434

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