A Conserved Motif in the Linker Domain of STAT1 Transcription Factor Is Required for Both Recognition and Release from High-Affinity DNA-Binding Sites

Binding to specific palindromic sequences termed gamma-activated sites (GAS) is a hallmark of gene activation by members of the STAT (signal transducer and activator of transcription) family of cytokine-inducible transcription factors. However, the precise molecular mechanisms involved in the signal...

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Detalles Bibliográficos
Autores principales: Hüntelmann, Bettina, Staab, Julia, Herrmann-Lingen, Christoph, Meyer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029728/
https://www.ncbi.nlm.nih.gov/pubmed/24847715
http://dx.doi.org/10.1371/journal.pone.0097633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029728/
https://www.ncbi.nlm.nih.gov/pubmed/24847715
http://dx.doi.org/10.1371/journal.pone.0097633

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