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Deletion of Nardilysin Prevents the Development of Steatohepatitis and Liver Fibrotic Changes

Nonalcoholic steatohepatitis (NASH) is an inflammatory form of nonalcoholic fatty liver disease that progresses to liver cirrhosis. It is still unknown how only limited patients with fatty liver develop NASH. Tumor necrosis factor (TNF)-α is one of the key molecules in initiating the vicious circle...

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Detalles Bibliográficos
Autores principales: Ishizu-Higashi, Shoko, Seno, Hiroshi, Nishi, Eiichiro, Matsumoto, Yoshihide, Ikuta, Kozo, Tsuda, Motoyuki, Kimura, Yoshito, Takada, Yutaka, Kimura, Yuto, Nakanishi, Yuki, Kanda, Keitaro, Komekado, Hideyuki, Chiba, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029810/
https://www.ncbi.nlm.nih.gov/pubmed/24849253
http://dx.doi.org/10.1371/journal.pone.0098017