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Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients

High-risk neuroblastoma is an aggressive malignancy with high rates of treatment failure. We evaluated genetic variants associated with in vitro sensitivity to two derivatives of cyclophosphamide for association with clinical response in a separate replication cohort of neuroblastoma patients (n=2,7...

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Detalles Bibliográficos
Autores principales: Pinto, Navin, Gamazon, Eric R., Antao, Nirav, Myers, Jamie, Stark, Amy L., Konkashbaev, Anuar, Im, Hae Kyung, Diskin, Sharon J., London, Wendy B., Ludeman, Susan M., Maris, John M., Cox, Nancy J., Cohn, Susan L., Dolan, M. Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029857/
https://www.ncbi.nlm.nih.gov/pubmed/24549002
http://dx.doi.org/10.1038/clpt.2014.37