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Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients
High-risk neuroblastoma is an aggressive malignancy with high rates of treatment failure. We evaluated genetic variants associated with in vitro sensitivity to two derivatives of cyclophosphamide for association with clinical response in a separate replication cohort of neuroblastoma patients (n=2,7...
Autores principales: | Pinto, Navin, Gamazon, Eric R., Antao, Nirav, Myers, Jamie, Stark, Amy L., Konkashbaev, Anuar, Im, Hae Kyung, Diskin, Sharon J., London, Wendy B., Ludeman, Susan M., Maris, John M., Cox, Nancy J., Cohn, Susan L., Dolan, M. Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029857/ https://www.ncbi.nlm.nih.gov/pubmed/24549002 http://dx.doi.org/10.1038/clpt.2014.37 |
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