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Dissecting the Critical Factors for Thermodynamic Stability of Modular Proteins Using Molecular Modeling Approach

Repeat proteins have recently attracted much attention as alternative scaffolds to immunoglobulin antibodies due to their unique structural and biophysical features. In particular, repeat proteins show high stability against temperature and chaotic agents. Despite many studies, structural features f...

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Detalles Bibliográficos
Autores principales: Lee, Yuno, Lee, Joong-jae, Kim, Songmi, Lee, Sang-Chul, Han, Jieun, Heu, Woosung, Park, Keunwan, Kim, Hyun Jung, Cheong, Hae-Kap, Kim, Dongsup, Kim, Hak-Sung, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029881/
https://www.ncbi.nlm.nih.gov/pubmed/24849801
http://dx.doi.org/10.1371/journal.pone.0098243