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Dissecting the Critical Factors for Thermodynamic Stability of Modular Proteins Using Molecular Modeling Approach
Repeat proteins have recently attracted much attention as alternative scaffolds to immunoglobulin antibodies due to their unique structural and biophysical features. In particular, repeat proteins show high stability against temperature and chaotic agents. Despite many studies, structural features f...
Autores principales: | Lee, Yuno, Lee, Joong-jae, Kim, Songmi, Lee, Sang-Chul, Han, Jieun, Heu, Woosung, Park, Keunwan, Kim, Hyun Jung, Cheong, Hae-Kap, Kim, Dongsup, Kim, Hak-Sung, Lee, Keun Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029881/ https://www.ncbi.nlm.nih.gov/pubmed/24849801 http://dx.doi.org/10.1371/journal.pone.0098243 |
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