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Single Strain Isolation Method for Cell Culture-Adapted Hepatitis C Virus by End-Point Dilution and Infection

The hepatitis C virus (HCV) culture system has enabled us to clarify the HCV life cycle and essential host factors for propagation. However, the virus production level of wild-type JFH-1 (JFH-1/wt) is limited, and this leads to difficulties in performing experiments that require higher viral concent...

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Detalles Bibliográficos
Autores principales: Sugiyama, Nao, Murayama, Asako, Suzuki, Ryosuke, Watanabe, Noriyuki, Shiina, Masaaki, Liang, T. Jake, Wakita, Takaji, Kato, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029950/
https://www.ncbi.nlm.nih.gov/pubmed/24848954
http://dx.doi.org/10.1371/journal.pone.0098168