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Maternal Obesity Reduces Milk Lipid Production in Lactating Mice by Inhibiting Acetyl-CoA Carboxylase and Impairing Fatty Acid Synthesis

Maternal metabolic and nutrient trafficking adaptations to lactation differ among lean and obese mice fed a high fat (HF) diet. Obesity is thought to impair milk lipid production, in part, by decreasing trafficking of dietary and de novo synthesized lipids to the mammary gland. Here, we report that...

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Detalles Bibliográficos
Autores principales: Saben, Jessica L., Bales, Elise S., Jackman, Matthew R., Orlicky, David, MacLean, Paul S., McManaman, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029960/
https://www.ncbi.nlm.nih.gov/pubmed/24849657
http://dx.doi.org/10.1371/journal.pone.0098066