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Maternal Obesity Reduces Milk Lipid Production in Lactating Mice by Inhibiting Acetyl-CoA Carboxylase and Impairing Fatty Acid Synthesis
Maternal metabolic and nutrient trafficking adaptations to lactation differ among lean and obese mice fed a high fat (HF) diet. Obesity is thought to impair milk lipid production, in part, by decreasing trafficking of dietary and de novo synthesized lipids to the mammary gland. Here, we report that...
Autores principales: | Saben, Jessica L., Bales, Elise S., Jackman, Matthew R., Orlicky, David, MacLean, Paul S., McManaman, James L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029960/ https://www.ncbi.nlm.nih.gov/pubmed/24849657 http://dx.doi.org/10.1371/journal.pone.0098066 |
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