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Recombinant tandem multi-linear neutralizing epitopes of human enterovirus 71 elicited protective immunity in mice
BACKGROUND: Human Enterovirus 71 (EV71) has emerged as the leading cause of viral encephalitis in children, especially in the Asia-Pacific regions. EV71 vaccine development is of high priority at present, and neutralization antibodies have been documented to play critical roles during in vitro and i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030048/ https://www.ncbi.nlm.nih.gov/pubmed/24885030 http://dx.doi.org/10.1186/1743-422X-11-79 |