Abnormal expression of an ADAR2 alternative splicing variant in gliomas downregulates adenosine-to-inosine RNA editing

BACKGROUND: RNA editing is catalyzed by adenosine deaminases acting on RNA (ADARs). ADAR2 is the main enzyme responsible for recoding editing in humans. Adenosine-to-inosine (A-to-I) editing at the Q/R site is reported to be decreased in gliomas; however, the expression of ADAR2 mRNA was not greatly...

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Detalles Bibliográficos
Autores principales: Wei, Jun, Li, Zhaohui, Du, Chao, Qi, Bin, Zhao, Xingli, Wang, Liping, Bi, Lirong, Wang, Guan, Zhang, Xuan, Su, Xiaoyun, Pan, Yuzhuo, Tian, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2014
Materias:
Experimental research - Brain Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030101/
https://www.ncbi.nlm.nih.gov/pubmed/24509948
http://dx.doi.org/10.1007/s00701-014-2004-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030101/
https://www.ncbi.nlm.nih.gov/pubmed/24509948
http://dx.doi.org/10.1007/s00701-014-2004-1

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