Epidermal Growth Factor Receptor Inhibition Slows Progression of Diabetic Nephropathy in Association With a Decrease in Endoplasmic Reticulum Stress and an Increase in Autophagy

Previous studies by us and others have reported renal epidermal growth factor receptors (EGFRs) are activated in models of diabetic nephropathy. In the present study, we examined the effect of treatment with erlotinib, an inhibitor of EGFR tyrosine kinase activity, on the progression of diabetic nep...

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Detalles Bibliográficos
Autores principales: Zhang, Ming-Zhi, Wang, Yinqui, Paueksakon, Paisit, Harris, Raymond C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030104/
https://www.ncbi.nlm.nih.gov/pubmed/24705402
http://dx.doi.org/10.2337/db13-1279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030104/
https://www.ncbi.nlm.nih.gov/pubmed/24705402
http://dx.doi.org/10.2337/db13-1279

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