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Probing the global and local dynamics of aminoacyl-tRNA synthetases using all-atom and coarse-grained simulations

Coarse-grained simulations have emerged as invaluable tools for studying conformational changes in biomolecules. To evaluate the effectiveness of computationally inexpensive coarse-grained models in studying global and local dynamics of large protein systems like aminoacyl-tRNA synthetases, we have...

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Detalles Bibliográficos
Autores principales: Strom, Alexander M., Fehling, Samuel C., Bhattacharyya, Sudeep, Hati, Sanchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030129/
https://www.ncbi.nlm.nih.gov/pubmed/24810463
http://dx.doi.org/10.1007/s00894-014-2245-1