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Estrogen Signaling and the DNA Damage Response in Hormone Dependent Breast Cancers
Estrogen is necessary for the normal growth and development of breast tissue, but high levels of estrogen are a major risk factor for breast cancer. One mechanism by which estrogen could contribute to breast cancer is via the induction of DNA damage. This perspective discusses the mechanisms by whic...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030134/ https://www.ncbi.nlm.nih.gov/pubmed/24860786 http://dx.doi.org/10.3389/fonc.2014.00106 |