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Estrogen Signaling and the DNA Damage Response in Hormone Dependent Breast Cancers

Estrogen is necessary for the normal growth and development of breast tissue, but high levels of estrogen are a major risk factor for breast cancer. One mechanism by which estrogen could contribute to breast cancer is via the induction of DNA damage. This perspective discusses the mechanisms by whic...

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Detalles Bibliográficos
Autor principal: Caldon, C. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030134/
https://www.ncbi.nlm.nih.gov/pubmed/24860786
http://dx.doi.org/10.3389/fonc.2014.00106