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Block of T-type calcium channels by protoxins I and II

BACKGROUND: Low-voltage-activated (T-type) calcium channels play a crucial role in a number of physiological processes, including neuronal and cardiac pacemaker activity and nociception. Therefore, finding specific modulators and/or blockers of T-type channels has become an important field of drug d...

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Detalles Bibliográficos
Autores principales: Bladen, Chris, Hamid, Jawed, Souza, Ivana A, Zamponi, Gerald W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030284/
https://www.ncbi.nlm.nih.gov/pubmed/24886690
http://dx.doi.org/10.1186/1756-6606-7-36