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FLAP pharmacological blockade modulates metabolism of endogenous tau in vivo 

FLAP (5-lipoxygenase-activating protein) is a protein widely distributed within the central nervous system whose function is to regulate the activation of the 5-Lipoxygenase enzyme. Although previous works show that pharmacological blockade of FLAP improve the amyloidotic phenotype of the Tg2576, it...

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Detalles Bibliográficos
Autores principales: Chu, J, Lauretti, E, Meco, A Di, Praticò, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030325/
https://www.ncbi.nlm.nih.gov/pubmed/24301651
http://dx.doi.org/10.1038/tp.2013.106