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Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases

Latrepirdine (Dimebon(TM)) was originally marketed as a non-selective antihistamine in Russia. It was repurposed as an effective treatment for patients suffering from Alzheimer's disease (AD) and Huntington's disease (HD) following preliminary reports showing its neuroprotective functions...

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Detalles Bibliográficos
Autores principales: Bharadwaj, P R, Bates, K A, Porter, T, Teimouri, E, Perry, G, Steele, J W, Gandy, S, Groth, D, Martins, R N, Verdile, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030329/
https://www.ncbi.nlm.nih.gov/pubmed/24301650
http://dx.doi.org/10.1038/tp.2013.97